We calculated distance with our calculator and with the help of International map agencies and distance between Hauptbahnhof Karlstraße Frankfurt am Main and Frankfurt Airport long distance Station is 120 km.
If you go from Hauptbahnhof Karlstraße Frankfurt am Main to Frankfurt Airport long distance Station, with normal traffic conditions and non-stop driving, you reach final destination in 1,5 hours.
Depend on car conditions and fuel quality, to travel from Hauptbahnhof Karlstraße Frankfurt am Main to Frankfurt Airport long distance Station with car transport, you need 7 gallons gallons of petrol, which will cost around 10 $ with average prices.